Whether you're freezing for the future or starting IVF, every egg is precious.

Opal™ provides a clearer understanding of egg quality — helping guide smarter, more confident decisions at one of the most important moments in your care.

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Because “Good-Looking” Isn’t Always Good Enough

Until now, egg quality has been evaluated mostly by appearance. But appearance doesn’t tell the whole story.

Opal adds another layer of insight with a more systematic and consistent evaluation standard.

Opal: A New Standard in Egg Quality Assessment

Opal™ is the world’s first device designed to assess egg quality by measuring both:

  • Morphological features (appearance)
  • Viscoelastic properties (response to gentle pressure)

Using a clinically validated predictive model, Opal assigns each egg a standardized grade: A, B, or C.


With Opal, your care team can:

  • Objectively identify eggs with the highest potential
  • Make more informed fertilization decisions – without additional procedures for you
  • Use those insights to guide future treatment decisions if needed


Even the Most Skilled Labs Face Uncertainty

Egg quality plays a central role in:

  • Fertilization rate
  • Blastocyst formation
  • Implantation success

But current methods remain largely subjective, relying heavily on appearance alone.

In real clinical settings, that uncertainty is compounded by:

  • Regulatory fertilization limits
  • Biological variability between patients
  • High egg yield but low pregnancy rates (e.g., PCOS)

When the stakes are high, additional objective insight can make a difference.

Higher-grade eggs identified by Opal have been associated with:

  • Higher fertilization rates
  • Higher blastocyst formation rates
  • Better reproductive outcomes



Seamlessly Integrated Into the IVF Lab

Opal is used immediately after egg retrieval and before fertilization or freezing. The analysis takes just 5–7 seconds per egg, and is performed entirely by trained embryologists in the lab.


The Process:

No extra steps for you.
No changes to your protocol.
Just better information at one of the most important moments.

Understanding Your Results

After Opal analysis, each egg receives a grade.

Highest likelihood of forming a blastocyst

Moderate likelihood of forming a blastocyst

Lower likelihood of forming a blastocyst compared to A and B grades

Opal then generates a visual report to support clinician–patient discussions and decision-making.

Your doctor interprets these results within your full clinical picture — because no single metric defines your journey.

When Is Opal Used?

Egg Freezing

Used immediately after egg retrieval to help determine whether additional retrieval cycles may be beneficial. 


Supports:

  • Social freezing
  • Fertility preservation
  • Egg donation


IVF Treatment

Can assess:

  • Fresh eggs
  • Previously frozen eggs after thawing


In regions with fertilization limits or complex cases, Opal supports selection of the eggs with the best potential for becoming healthy blastocysts.

When working with multiple euploid embryos or Day 3 embryos that won't go through PGT-A testing, traceable egg grading may help prioritize embryos for transfer.

Who Has the Most to Gain From Opal?

A History of Failed Implantation or Miscarriage

Patients with Low AMH

Patients with PCOS

Safety & Clinical Validation

Clinical studies confirm Opal is:

  • Non-invasive
  • Does not negatively affect fertilization
  • Does not impair embryo development


Validated through IRB-approved, multi-center studies and built to strict ethical and data privacy standards.