The window of implantation (WOI) is the specific time frame when the endometrium is most receptive to embryo implantation. Most women’s WOI falls within a standard range. However, about 20% of women under age 38 and 30% of women over age 38 have a displaced WOI.
ora® is a non-invasive endometrial receptivity assay test designed to identify the optimal window of implantation (WOI) for embryo transfer during IVF treatment.
For those undergoing IVF treatment, accurately identifying your individual WOI is critical to improving success rates. Personalized assessment of endometrial receptivity allows clinicians to optimize embryo transfer timing and increase the likelihood of implantation and pregnancy.
ora® stands out as the only non-invasive test of its type, requiring only a simple blood draw, instead of an endometrial biopsy.
ora® Reserve helps reduce unnecessary mock IVF cycle—saving time, emotional strain, and treatment costs.
Over 60% success rate in patients with previous implantation failures—backed by data and real-world outcomes (see below).
ora® uses a non-invasive blood test to—no need for painful endometrial biopsies.
Compared to traditional endometrial receptivity arrays, ora® stands out with its stability and superior pregnancy rates. Clinicians trust ora® for enhanced patient outcomes.
Pregnancy Success Rates
It is particularly beneficial for those who have experienced challenges in achieving successful IVF outcomes. For these patient groups, ora® leads to a higher implantation success rate.
For first-time IVF patients, we recommend ora® Reserve, a sample storage service that makes future ora® testing, if required, more efficient and cost-effective.
A mock cycle is a simulated IVF cycle used to prepare the endometrium and collect a sample for endometrial receptivity testing. It helps identify the optimal WOI without transferring an embryo, allowing for precise timing in future IVF cycles.
Patients using ora® Reserve have their sample collected during a previous complete IVF cycle and do not require a mock cycle.
No, ora® Reserve is an optional sample storage service to enhance the efficiency of ora® on a future cycle. It is intended primarily for first-time IVF patients. Any IVF patient may choose to go directly to ora® testing by undergoing a mock cycle.
Research shows that human cells release specific signaling factors (such as microRNA), which travel through the bloodstream to facilitate communication between different organs and cells throughout the body. By detecting specific microRNAs in the blood, we can understand physiological changes, including whether the endometrium has entered its optimal implantation window (WOI).
Embryo transfer typically occurs 3 to 5 days after egg retrieval. The exact timing depends on the development stage of the embryos:
Implantation usually occurs 1 to 5 days after a blastocyst transfer. If the embryo is transferred at an earlier stage, such as the cleavage stage, implantation can occur 6 to 10 days after egg retrieval.
For more information, download our brochure, explore our research and white papers, or contact Inti with any questions. Talk to your doctor about ora® early in your treatment.